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Research & Education

Presentations

Research at The WA PET/Cyclotron Service

One of the major aims of the Service is the development of a wide-ranging clinical and basic science research programme to optimise the facilities and expertise available.

The research programme is structured into 3 major areas:

  1. Clinical PET
  2. New Radiopharmaceutical Development
  3. Solid Targetry

The facility has the benefit of 5 hot cells in a GMP (Good Manufacturing Practice) facility with a further research hot cell and radio-labelling fume hood situated within the radiopharmaceutical production laboratory. This area is equipped with state of the art quality control apparatus and further research laboratories are also available elsewhere in the facility. We have the benefit of two highly skilled radiochemists to help with not only routine commercial FDG production but also new radiopharmaceutical development.

The cyclotron facility is staffed with physicists and technicians trained in PET and cyclotron technology from the Department of Medical Technology and Physics This Department has the strong technical/engineering background crucial to such areas as solid targetry development.
Within the PET Service there is also the availability for in depth data and clinical trial management with staff having expertise in these areas as well as experienced technologists and nursing staff.

Finally the facility has formal ties to the Western Australian Institute of Medical Research, The Western Australian Co-operative Oncology Group, The Western Biomedical Research Institute of Medical and the Institute of Radiochemical Engineering (IRE) with representatives from these groups being part of the Management Committee for the Service. Formal collaboration with the Cyclotron company, IBA (Ion Beam Applications) has begun. Further collaborations with the PET facilities around Australia are also envisaged.

Current Research Projects:

  1. Commonwealth Data Collection Process
  2. PET in atherosclerosis
  3. FDG-PET and recombinant TSH in thyroid cancer
  4. Development of C-11 methionine, F-18 FLT and F-18 fluorocholine
  5. Solid targetry development (I-123/I-124; Cu-62/Cu-64)
  6. SPN staging – both retrospective review and prospective clinical trials
  7. FDG-PET in restaging of breast cancer
  8. PET in the staging of lymphoma and sarcoma in paediatrics as compared to Gallium scans.
  9. F-18 Bone scans in Breast Cancer

Postgraduate Students:

  1. Solid target Synthesis of Iodine and Cu isotopes.
  2. Tc-96 for radioactive stents
  3. Neutron Dosimetry

Presentations and Publications

Presentations

2004

“Radioisotope and Radiopharmaceutical Production for Positron Emission Tomography, Post commissioning”

Presenter: Mr Thomas Tuchyna
ANZSNM Annual Scientific Meeting Wellington New Zealand

“Diazepam for "Muscle Activity" in FDG PET“

Dr Nat Lenzo, Dr Gerry Moschilla, Dr Petter Tonseth, Mrs Kerryn Butler-Henderson, Ms Penny Maton
ANZSNM Annual Scientific Meeting Wellington New Zealand

“FDG PET in Pancreatic Lesions : Preliminary Findings”

Dr Nat Lenzo, Dr Petter Tonseth, Dr Michael McCarthy, Mrs Kerryn Butler-Henderson, Ms Penny Maton.
ANZSNM Annual Scientific Meeting Wellington New Zealand

“FDG PET in Presumed early Non-small Cell Lung Cancer”

Dr Nat Lenzo, Dr Petter Tonseth, Dr Marina Dunne, Mrs Kerryn Butler-Henderson, Mrs Julie Crouch
ANZSNM Annual Scientific Meeting Wellington New Zealand

2003

“Status report of a radioisotope and a radiopharmaceutical production facility for PET”

ANZSNM Annual Scientific Meeting Sydney
Presenter: Mr Thomas Tuchyna

“Establishing a PET service in a remote city of Australia”

ANZSNM Annual Scientific Meeting Sydney
Presenter: Mrs Julie Crouch

Posters

2004

”Occult Hepatic Neoplasms Detected by FDG PET”

Dr Nat Lenzo, Dr. Petter Tonseth, Mrs Julie Crouch
ANZSNM Annual Scientific Meeting Wellington New Zealand

“HMPAO SPECT, FDG PET and Anatomical Imaging in Patients with Linguistic Disorders”

Dr. Michael McCarthy, Dr. Andrew Campbell. Dr. Nat Lenzo, Ms Joanne Thompson, Dr. Peter Panegyres
ANZSNM Annual Scientific Meeting Wellington New Zealand

“Automatic PET – CT Image Registration: Emission or Transmission”

Dr. M McCarthy, Dr. A Campbell, Dr, N Lenzo
ANZSNM Annual Scientific Meeting Wellington New Zealand

2003

“CT Negative Osseous Lymphoma – Benefit of FDG-PET”

ANZSNM Annual Scientific Meeting Sydney
Mrs. J. Crouch, Dr N.P. Lenzo, Dr. A. Patrikeos, Dr. P. Robins

Publications

2004

“Diffuse splenic metastasis from seminoma visualised by FDG PET.”

(American Journal of Roentgenology. 2004 Aug;183(2):525-7)
Authors: Dr N Lenzo, Dr Gerry Moschilla and Dr A Patrikeos